NIAID Cell Ontology Workshop May 2008
The NIAID sponsored a Cell Ontology Workshop, May 13-14, 2008, in Bethesda, focusing on improving representation of immune cell types in the Cell Ontology. The participants in the workshop worked together to extend the current ontology in the area of immune cell types and to provide the necessary information for the upcoming restructuring of the Cell Ontology in single-inheritance form with genus-differentia definitions.
Summary of Workshop Proceedings
Graphical Views of Hematopoietic Cells in the Cell Ontology (May 2008)
T Cells
B Cells
Natural Killer Cells
Dendritic Cells
Macrophages and Osteoclasts
Granulocytes and Mast Cells
Erythrocytes and Platelets
Slide Presentations from Meeting
A_Diehl_Cell_Ontology_Workshop_Introduction
R_Scheuermann_Cell_Ontology_Intro
Cell Ontology Workshop Follow Up Conference Calls, July-August 2008
T Cells: July 24, 3:30 PM-4:30 PM ET (Discussion leader: Penny Morel)
T_cell_ontology_revisions.ppt
T_cell_ontology.obo (T cell and NK revisions, last revised 8-20-08)
Macrophages: Friday, August 1st., 2:00 PM-3:00 PM ET (Discussion leaders: Anastasia Nijnik and Elizabeth Gold)
Macrophage_ontology_revision.pdf
Macrophage_ontology_revisions.obo (added a bogus .doc extension to get this to load into the wiki)
Dendritic Cells: Tuesday, August 19, 3:00 PM-4:00 PM ET (Discussion leaders: Lindsay Cowell and Anna Maria Masci)
Revised Dendritic Cells.pdf
NK Cells: Thursday, August 21, 3:00 PM-4:00 PM ET (Discussion leader: Alex Diehl and Penny Morel)
T_cell_ontology.obo (T cell and NK revisions, same file as above, last revised 8-20-08)
B Cells: Thursday, August 21, 4:30 PM - 5:30 PM ET (Discussion leader: Martin Zand)
Important Links
Cell Type Ontology page on the Modeling Immunity for Biodefense WIki (requires approval)
Leukocyte Surface Marker Ontology (cdo.obo, created by Martin Zand)
An Excel spreadsheet of current immune and hematopoietic cell types in the Cell Ontology can be found here. This spreadsheet has columns for additional descriptive information for the existing immune cell types that participants are invited to fill in as they like: proper is_a parent, morphology, surface markers, transcription factors, location, role or process, and lineage. This information will be used in constructing formal definitions for these cell types.