OBD:Use Cases

1. I'm a curator and have come across a new term in a manuscript that I think maybe I should use for an annotation. I wonder whether the term is already in some ontology or whether it has a synonym that I should use. I'm not even sure which ontology to check. [goto Case1 notes]
2. An author makes a statement about an anatomical relationship (part_of) in mouse that's different than what I understand for fish. I want to explore this part of mouse anatomy. [goto Case2 notes]
3. I have a mutation in a gene in fly which has a heart defect. I want to know what other genes in other organisms have a similar defect and their similarity in sequence or not to my gene - i.e. query by defect. [goto Case3 notes]
4. I work for a company that is starting to use microarrays that are annotated with GO terms. I want to learn what human diseases and animals models are represented on the chip.
5. I have a bag of probes which are apparently upregulated under a given set of conditions (from a microarray experiment). Are there any similarities among these with respect to their mutant phenotypes?
6. I want to mine PubMed abstracts for papers which are 'about' a specific phenotypic defect. How can I use PATO to help me do this effectively?
7. I have the sequence of a gene in fly. I want to know what other genes in other organisms have similar sequences, and what their phenotype are - i.e. query by sequence.
8. We want to visualize key information about a clinical trial in a slick and useful way.
9. We need to determine whether a completed trial is relevant to a particular patient (eitehr eligible for or relevant to their condition by querying with key information about that patient. If the clinical information is deposited into OBD in MeSH or UMLS format, then Mayo's vocab mapping services will return the best mapping(s) to SNOMED-CT or ICD9 or some other (perhaps arbitrarily defined) vocabulary.